This paper describes how the Smart City paradigm can be successfully changed into the “Smart Region” concept as happened in the Piedmont Region. Different projects and technologies involved in this perspective change will be described through the genesis of the unified Centro Servizi Regionale (CSR), embodiment of the Mobility as a Service approach. CSR is not only an arrival point of this vision but it will also be the starting point of new epochal changes: its future improvements will be reported.